ISAAC TRIMBLE was born in Livingston County, Ky., December 4, 1810. His ancestors were South Carolinians and of English descent. His father, James Trimble, settled in what is now Crittenden County, in 1803, near the Sulphur Springs, where he engaged in farming. He was also a wagon-maker during the early years of his life among the pioneer settlements of Livingston County, where he died in about 1808. Margaret (Gillespie) Trimble, subject's mother, was a daughter of William Gillespie of South Carolina. She died in Livingston County in 1855, at the age of about sixty years. Isaac is the youngest of a family of five children, and is the only one living. His life has been spent within the limits of his native county, where for seventy-four years he has been an honored and respected citizen. At the age of two years he was bereft of his father, and at seventeen commenced life for himself as a farmer. He purchased a part of the home farm, on which he lives, soon after arriving at manhood, and has never resided in any other locality. He commenced business without a cent in his pocket, but such was his energy, that by the time he was twenty-one years of age he had saved sufficient capital to enable him to make a fair start in the world. He now owns a beautiful tract of land in Carrsville Precinct, consisting of 400 acres, 200 of which are under a good state of cultivation. October 1, 1833, Mr. Trimble was married to Jane Hosick, daughter of Alexander and Hannah (Wilson) Hosick. The fruits of this marriage were nine children, named as follows: James A., Clarissa (deceased), Narcissa, Sarah C. (deceased), William J. (deceased), Hannah L., Uriah, Margaret and Benjamin F. Mrs. Trimble died in 1851. Six years later, on December 18th, Mr. Trimble's second marriage was solemnized with Miss Mary Barnes, daughter of James and Tempy Barnes of Crittenden County. This union has been blessed with three children: Mary E., Luella (deceased), and Cordelia. Mr. Trimble has been a consistent and active member of the Methodist Church South, for a period of about forty years.
Source: J. H. Battle, W. H. Perrin, & G. C. Kniffin. Kentucky. A History of the State. Louisville, KY, Chicago, IL: Battey, 1885. Page 837.